Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.

¹æ»ç¼±Á¶»ç¿¡ µû¸¥ ±¸°³Á¡¸·»óÇÇÀÇ ÇüÅÂÇÐÀû º¯È­¿¡ °üÇÑ ½ÇÇèÀû ¿¬±¸

AN EXPERIMENTAL STUDY OF THE RADIATION-INDUCED CHANGES IN THE EPITHELIUM OF THE RAT PALATAL MUCOSAE

Ä¡°ú¹æ»ç¼± 1994³â 24±Ç 2È£ p.327 ~ 336
¼±°æ, ÃÖÈ£¿µ, ¹Ú»óÁø, Á¤Àç¹Î,
¼Ò¼Ó »ó¼¼Á¤º¸
¼±°æ (  ) - °æºÏ´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°ú¹æ»ç¼±ÇÐ
ÃÖÈ£¿µ (  ) - °æºÏ´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°ú¹æ»ç¼±ÇÐ
¹Ú»óÁø (  ) - °æºÏ´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°ú¹æ»ç¼±ÇÐ
Á¤Àç¹Î (  ) - °æºÏ´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°ú¹æ»ç¼±ÇÐ

Abstract

±¸°³Á¡¸·»óÇÇ¿¡¼­ ¹æ»ç¼±Á¶»ç·®°ú ½ÃÀÏ°æ°ú¿¡ µû¸¥ º¯È­¸¦ ¾Ë¾Æº¸±â À§ÇÏ¿©, ¹é¼­ µÎ°æºÎ
¿¡ 6MV X¼±À» 5Gy¹× 10GyÁ¶»çÇÏ°í Á¶Á÷ÇÐÀû º¯È­¸¦ °üÂûÇÏ¿© ´ÙÀ½ÀÇ °á°ú¸¦ ¾ò¾ú´Ù.
¹æ»ç¼±Á¶»çÈÄ 3½Ã°£±º°ú 6½Ã°£±º¿¡¼­ ¼öÆ÷¼ºº¯È­¿Í »óÇÇÃþ µÎ²²ÀÇ °¨¼Ò°¡ °üÂûµÇ¾ú°í, 3
Àϱº¿¡¼­´Â ±âÀú¼¼Æ÷ÀÇ Áõ½ÄÀ¸·Î ÀÎÇÑ »óÇÇÃþÀÇ µÎ²² Áõ°¡¿Í »óÇÇÀ¶±âÀÇ ½ÅÀåÀÌ °üÂûµÇ¾ú
´Ù. °æ±¸°³ºÎÀ§ÀÇ Á¡¸·»óÇÇ¿¡¼­´Â 5GyÁ¶»çÈÄ 7Àϱº¿¡¼­, 10GyÁ¶»çÈÄ 14Àϱº¿¡¼­ ȸº¹µÇ´Â
¼Ò°ßÀ» º¸¿´°í, ¿¬±¸°³ºÎÀ§ÀÇ Á¡¸·»óÇÇ¿¡¼­´Â 5GyÁ¶»çÈÄ 14Àϱº¿¡¼­, 10GyÁ¶»çÈÄ 28Àϱº¿¡
¼­ ȸº¹µÇ´Â ¼Ò°ßÀ» º¸¿´´Ù. ¶ÇÇÑ °æ±¸°³ºÎÀ§¿¡ ºñÇØ ¿¬±¸°³ºÎÀ§ÀÇ Á¡¸·»óÇÇ¿¡¼­ ¹æ»ç¼±Á¶
»ç·Î ÀÎÇÑ Á¶Á÷¹ÝÀÀÀÌ º¸´Ù ºÐ¸íÇÏ¿´°í, ȸº¹µµ Áö¿¬µÇ¾ú´Ù.
#ÃÊ·Ï#
The purpose of this study was to investigate the irradiation effects on the palatal
mucosa. For this study, Sprague-Dawley strain rats were irradiated to their head and
neck region with the dose of 5Gy and 10Gy by 6MV X-radiation and sacrificed on the
experimental periods after irradiation. The authors observed the histological changes of
the hard and soft palatal mucosae.
The results were as follows:
In the light microscopic examination, hydropic change on the basal cells, increased cell
size of the epithelium, and decreased epithelial cell layers were observed on the
3hours,6hours, and 12hours groups after irradiation. But, basal cell hyperplasia, increased
epithelial cell layers, and elongated rete pegs were observed on the 3days group after
irradiation. After then, these changes were recovered in the mucosa of the hard palate
on the 7days and 14days groups, and in the mucosa of the soft palate on the 14days
and 28days groups after irradiation. And such changes were greater in the mucosa of
the soft palate than in that of the hard palate, and more prominent in 10Gy irradiated
groups than in 5Gy irradiated groups.

Å°¿öµå

¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸

  

µîÀçÀú³Î Á¤º¸